ORAL PEMPHIGUS VULGARIS: A CASE REPORT

  • Radha Baral Kantipur Dental College
  • Bidhata Ojha
  • Dipshikha Bajracharya
Keywords: Acantholysis, Desmoglin 3, Pemphigus vulgaris

Abstract

Pemphigus vulgaris is an autoimmune blistering disease clinically presenting as vesicles, bullae and erosion on the skin and mucous membrane. Histopathologically, it is characterized by acantholy­sis and supra basilar split. The underlying mechanism causing intra epithelial split in pemphigus vulgaris is binding of IgG autoantibodies to desmoglin 3 which belongs to a transmembrane gly­coprotein adhesion molecule. Here we present a case of 27 years old male patient suffering from pemphigus vulgaris. This Case report highlights the importance of detailed case history, thorough clinical examination and appropriate investigation to reach a diagnosis of vesiculobullous lesion.

Published
2020-03-14